Molecular Formula | C19H23NO3 |
Molar Mass | 313.39 |
Density | 1.21±0.1 g/cm3(Predicted) |
Boling Point | 476.3±45.0 °C(Predicted) |
Solubility | DMSO |
pKa | 12.75±0.20(Predicted) |
Storage Condition | -20℃ |
In vitro study | For antagonistic activity, (−)-mavoglurant, the (−)-enantiomer shows IC 50 of 0.11 μM and 0.03 μM (Ca 2+ and PI-turnover) whereas the (+)-enantiomer ((+)-10) shows only 37% and 18% inhibition at 10 μM. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.191 ml | 15.955 ml | 31.909 ml |
5 mM | 0.638 ml | 3.191 ml | 6.382 ml |
10 mM | 0.319 ml | 1.595 ml | 3.191 ml |
5 mM | 0.064 ml | 0.319 ml | 0.638 ml |